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SYDNEY, 2nd  MARCH, 2022 - Are you looking for the most affordable and reliable taxi service in Sydney on your next trip? Are you looking for a taxi service that is not only highly professional but also provides a unique and comfortable experience on your personal trip or business travel? Are you looking to take your friends and get away for a couple of days that's worth a relaxing drive? Are you looking for top-notch vehicles for private hire or corporate travel at really, really affordable pricing that would make your day? Then you are looking at the best choice you can make.

Infinite Cabs. Safe, reliable, comfortable and affordable is how passengers describe this service and choose every time they are looking for a taxi in Sydney. Whether to go to office or airport transfers or parcel delivery, and so much more! Infinite Cabs provides its riders with their preferred vehicles every single time. Even when you are planning a weekend getaway with friends, Infinite Cabs has your back. Just order a Maxi Cab and enjoy your journey. Choose to get picked from or dropped to the airport from a wide fleet of vehicles that are always on standby at the airport to receive you without you having to wait — every single time.

"Infinite Cabs gives you the most exquisite experience in travel to and from Sydney. It's not just about availability and affordability, which is of course eye-popping and amazing, it is about the top quality service that one can give you. We have a strict No Surge Pricing and No Hidden Cost Policy. Whether it is Airport Transfers, Business Travel or Parcel Delivery, Infinite Cabs provides the finest service you can get anywhere, free from the slightest worry. Looking for a getaway with friends or a personal trip? Try our Maxi Cab Service or the Platinum Service, whichever fits you. With a wide range of 7 seaters, 11 seaters and splendid luxurious cars at your service, Infinite Cabs is more than equipped to make your travel and your needs reach 100% satisfaction with our seamless service. Infinite Cabs is better than the best. Infinite Cabs is Perfection", said the CEO of Infinite Cabs.

About

Infinite Cabs is a taxi service that is based in Sydney, Australia. Its USP of No Surcharge and Safety Policy makes it the most subscribed taxi service.

Contact

Address - Unit 26, 532-536 Canterbury Road, Sydney NSW 2194

Phone Number - +61 1300103100

Website - https://infinitecabs.com.au/

Email - MAILinfo@infinitecabs.com.au

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Thomas Gilbert of Pressure Pros ENC, a Higher Bern, NC-based pressure washing company, has his sights set on new heights. But why power washing in Greenville? Thomas reports that thousands of homes and driveways are waiting to be power washed with 45 minutes of their home base. - source : (https://jscpressurewashing.com/new...g-greenville-nc/)

Easy Curb Appeal Trick: Power washing makes dirty houses look clean again.

Should your try to do this yourself or call a pro?

It just the logical thing to do, according to Thomas. "Pressure Pros ENC is a cost-effective solution to cleaning up any property exterior," he explains. For many folks, to pay $4,000 to have the exterior of their house painted is simply out of the question. Power washing your home and driveway, on the other hand, is a very cost-effective option.

Others simply do not want to waste a Saturday morning waiting in line at Home Depot to rent a pressure washer for $89 for a few hours. Frequently, the units are weak or malfunctioning. And by the time a homeowner has purchased the cleaners and degreasers, it is no longer worth their time. When compared to paying a few dollars extra to hire an insured power washing business to do it professionally..."

How can pressure washing a driveway, house or roof help you sell your home for more money?

According to real estate professionals, the resale market in the greater Greenville area is booming. According to Thomas, this means that homeowners will want to improve the appearance of their unclean sidewalks, driveways, and house siding. "In our opinion, there are three opportunities," he says. People who are flipping their old homes may wish to upgrade the curb appeal of their home in order to earn top cash for their property.

"Furthermore, there will be people who purchase resales as their primary residence. There will be those who want their roofs, patios, and decks pressure washed as a result of this. Finally, after a long winter, some folks will just wish to clean up their front and back yards. In either case, our low-cost pressure washing services in Greenville can assist customers in achieving their objectives."

"Pressure Pros ENC is creating a solid customer base in New Bern," Thomas continues. We hold a special place in our hearts for each and every one of them. Now we're excited to boost our marketing efforts in Greenville in order to find new customers. Visit https://ncpressurepros.business.site "

Media Contact:
Company Name: Pressure Pros ENC
Contact Person: Thomas Gilbert
Email: thomaswgilbert03@gmail.com

Phone: (252) 670-5086
Address:100 Wesley Dr
City: New Bern
State: NC
Country: United States
Website: https://jscpressurewashing.com/news/power-washing-greenville-nc/

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Feb 27 @ 9:52 am

After suffering a massive stroke, renowned crime fiction author, Jed Power, overcame his paralysis and wrote the eighth book in the acclaimed Dan Marlowe/Hampton Beach, NH, Crime/Mystery series. At the same time, Power completed a proposed TV Series Bible (explaining the proposal) and a Pilot episode adapting his series to a one-hour TV Series or feature film.  He is now looking for a Manager, Agent or producer to help with the project. Bible and/or Pilot are available on request.

Power admits that writing after a stroke had major obstacles. “Typing with one finger was the least of it,” Power said. He continued, “It brought me confidence, just getting it done. In my eyes anyhow, it was an accomplishment.”

CONTACT:  To learn more about Jed Power, the Dan Marlowe/Hampton Beach, NH, series, his proposed TV/Film adaptation, or to arrange an interview for a story, please contact:

Email:  jedpower@verizon.net

Facebook:  https://www.facebook.com/people/Jed-Power/

Phone:  978-979-2371

All eight Dan Marlowe/Hampton Beach, NH, books are available in paperback and eBook via Amazon, Barnes & Noble and most other outlets.

About Jed Power:  Jed Power is an acclaimed author, well known for his New Hampshire fiction crime series starring crime-solving lead character Dan Marlowe. Power suffered a devastating stroke in 2019 but returned to work after weeks in the hospital to finish the series' eighth book, The Treasure of Hampton Beach. He is presently writing a screenplay based on the series.

https://www.amazon.com/Treasure-Hampton-Beach-Marlowe-Mystery/dp/0997175869

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There's nothing quite like the feeling of riding a motorcycle on a summer day. A motorcycle ride can be a great way to experience the open road and enjoy the scenery. Motorcycle safety is important for both the rider and pillion. Motorcycle safety gear is important because it helps protect the rider in the event of an unfortunate incident. Most motorcycle accidents result in serious injury and motorcycle safety gear can help reduce the severity of these injuries.

It's important to choose the right motorcycle safety gear for your needs. For example, if you're riding in a cold climate, you'll need clothing that will keep you warm. If you're riding on a hot day, you'll need clothing that will keep you cool. And if you're riding on long trips, you'll need gear that is comfortable and will last all-day.

Resurgence gear’s safety gear that can help protect you include:

 - Motorcycle jacket

ROCKER JACKET: OLIVE

 - Gloves to protect your hands

VINTAGE AIM: BROWN GLOVES

 - Jeans to protect your legs

MENS JEANS: INDIGO SPORTS

 - Boots to protect your feet

  - Armor

 It's important to wear safety gear every time you ride your motorcycle, no matter how short the trip is. And make sure that your gear is the correct fit, so that it can provide the best protection possible.

A lot of people seem to think that it's not necessary, but it can be the difference between light to moderate or severe injuries.

Some other tips for staying safe on a motorcycle include:

1) Always ride with caution and be aware of your surroundings.

2) Never ride while impaired.

3) Use turn signals to let others know your intentions.

4) Keep your speed reasonable and don't weave in and out of traffic.

5) Avoid riding at night if possible.

6) Wear bright clothing so that others can see you.

7) Be aware of other riders and road users in their actions

8) Use caution when turning or changing lanes

9) Make sure your bike is in good working order before hitting the road

So make sure to always wear your protective gear when riding your motorcycle!

 

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Adhespack is a pioneer in the world to provide samples of perfumes and makeup with a surface protected against viruses and bacteria.

To offer greater security for those who are willing to go to one of its physical stores, O Boticário became the first company to use perfume and makeup samples with a surface protected against viruses and bacteria, developed by Adhespack , a pioneer in the world in antiviral sampling. 

“Since the beginning of the pandemic, we have been seeking to ensure a complete experience between the consumer and the brand, without losing emotion and our connection with the remarkable moments in the life of Brazilians, because our sector revolves around the sensorial, it passes through smell, touch ”, says Gustavo Fruges , director of brand experience at Grupo Boticário, who mentions other measures also adopted in stores, such as UVC equipment for cleaning tester products.

 
 
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Fruges explains that the group already offered the tags to customers for trial, with optional membership for the store. “The point of contact between hands and nose is very sensitive and responsible for the contagion, not only of Covid-19, but of other viral and bacterial diseases. Thus, the antiviral varnish was a great solution, as it avoids cross-contamination by contact with viruses and bacteria”. 

Proven effectiveness

Sergio Picciarelli , marketing and innovation director at Adhespack, says that samples with protection against viruses and bacteria were launched in September at Luxe Pack Monaco 2021. The product has undergone tests that meet two international standards (JIS Z 2801:2000 and ISO 21702:2019), which proved the effectiveness of the technology applied to the surface of the samples in preventing contamination by bacteria and viruses, including the Sars-CoV-2 alphacoronavirus, which is from the same family as the virus that causes Covid-19. 

The extra protection, according to the executive, can be applied to the standard Adhespack line, which already has the advantage of being safe, hygienic and individual. “The tests showed that viruses and bacteria are unable to attach or multiply on the surface of samples that received nanotechnology, minimizing the risks of cross-contamination in the event that a person shares their sample”, he guarantees. 

Sampling trends

Fruges believes that a strong trend is technologies that allow safe experimentation of products in the beauty market, guaranteeing an even more comfortable environment for consumers and store salespeople. The Group follows all safety protocols, such as handling products that are restricted to saleswomen, constant cleaning with 70 alcohol and the use of metallic plates and individual disposable brushes that make the experimentation of the products individualized. “Now, in an unprecedented way, we have launched a method capable of guaranteeing an even safer experimentation with the implementation of technology with high power ultraviolet C light for sterilization and disinfection of test products, including elimination of the Covid-19 virus from lipsticks and makeup that are used by clients”.

For the director of Grupo Boticário, the beauty sector is essentially sensorial, often depending on the delivery of these senses to choose the product. “Thus, we are preparing for this new reality in order to promote 100% safe shopping experiences. And this goes beyond products, as we want to make them responsibly, always taking care of everyone, from the beginning to the end of the process”. 

The antiviral label can be found in Grupo Boticário stores throughout Brazil that have opted for the technology. “Adhespack is at the forefront and has been offering safe, hygienic and individual solutions for a long time and has now developed a line with extra protection”, adds Picciarelli. 

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Washington, DC - February, 2022: Family Enterprise USA, an organization advocating for family businesses in Washington DC, has announced the addition of two new members to the company’s Board of Directors, Casey Roscoe and David Brown.

Casey Roscoe, after nearly two decades working in Washington, DC Casey decided to make good on a promise made to her grandfather to come work at her family’s company in 2016 as part of Seneca’s four-person Executive team. Casey’s family company was Seneca, which consists of four sawmills, 175,000 acres of sustainably managed timberlands, and an energy company that has the cleanest running biomass plant in America.

David Brown is President & CEO of Wyo-Ben, Inc., a 70-year-old family owned and family managed mining and manufacturing company.  The Company mines Sodium Bentonite, a clay based industrial mineral, in Wyoming and Montana    and processes it in its three Wyoming located plants into dozens of products for worldwide application in oil and gas exploration, metal casting, steel making, water treatment, cosmetics, pharmaceuticals, clumping cat litter, construction, and animal feeds, to name a few.

“We are excited to have Casey Roscoe and David Brown join as new Board Members of Family Enterprise USA. They will be excellent additions to the Board of Directors,” said Patricia M. Soldano, President of Family Enterprise USA. “Both Roscoe and Brown have extensive family business experience and have worked with members of Congress in the past representing family business in Washington DC.  

Family Enterprise USA represents family businesses of all sizes and within all industries. The organization has been praised and respected for its dedication to properly and constantly represent multigenerational family-owned businesses in DC. By adding Casey Roscoe and David Brown to the Board of Directors, Family Enterprise USA will expand its voice and efforts for family businesses. The new two board members have already begun working hard to help support these underrepresented communities in Washington DC.

About Family Enterprise USA
Family Enterprise USA promotes family business growth and their sustainability by advocating for family businesses and their lifetime of savings with Congress in Washington DC.  FEUSA represents all sizes and industries of family-owned enterprises and multi-generational businesses.

Contact: Pat Soldano; President, Family Enterprise USA; 714 357 3140
www.familyenterpriseusa.com

712 H Street NE

Suite 1330

Washington DC 20002

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WASHINGTON, D.C. – February, 2022 – Policy and Taxation Group (PATG), an organization dedicated to the ultimate repeal of estate, gift, and generation-skipping transfer (GST) taxes, is pleased to announce the addition of Jeff Michael and Angela B. Simmons to its Board of Directors.

Michael, the President of Corstar Goldings, Inc., a family-owned holding company and the largest shareholder of the CorVel Corporation, brings a wealth of experience to PATG. Michael has a master’s degree in Finance and Management Policy from the Northwestern University Kellogg School of Management and was previously the President and CEO of North Star Universal, Inc., a publicly owned holding company with investments in industrial and food processing businesses. Michael lives in Minnetonka, Minnesota and is responsible for directing investment activities for his multi-generational family.

Simmons is the owner and manager of ABD Legacy Partners, LLC. She holds a BA in Public Policy Studies from Duke University and has experience as an investment advisor, financial analyst, and portfolio manager. Simmons is a member of the Duke Women’s Impact Network, the James B. Duke Society, the Carolinas Family Office Forum and the Family Office Counsel and serves on the FOC Executive Committee. She is a Board member for the Beaver Family Foundation and Patrick Beaver Scholarship Foundation and is President of the TSH Charitable Foundation. She is located in Los Angeles, California.

“Taxes affect everyone – manufactures, retailers, restaurants, farms and businesses of all sizes, their employees, their children and grandchildren, and, more importantly, their very legacy,” said the Founder, President and Chairman of Policy and Taxation Group, Patricia M. Soldano. “Our work is to inform and educate legislators and staff, as well as, the executive branch and agencies about the destructive nature of established and proposed tax policies: the jobs that are eliminated, family livelihood lost, and the negative community impact.  We are honored to have Jeff Michael and Angela B. Simmons join our efforts.”

For more information about the strategic efforts of PATG to promote both short-term and long-term relief on Capitol Hill, to defeat harmful tax increases and provide practical leadership and community support visit policyandtaxationgroup.com.

About Policy and Taxation Group
Policy and Taxation Group (PATG) Policy and Taxation Group is the leading information, education and advocacy organization working for the reduction and ultimate elimination of estate, gift, and generation skipping transfer taxes, and other taxes that punish hard work and success. Our Mission is to challenge hostile tax policies that meaningfully and measurably impact families and limit the ability of family businesses to remain family owned.

Contact
Pat Soldano; President; Policy and Taxation Group
714 357 3140
https://policyandtaxationgroup.com/

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With 7777 Unique NFTs Honeybee collection from Beellionaire club is launching on Feb 25, 2022 on the Ethereum blockchain. Exclusive whitelist sale will become available on Feb 23, 2022.

 

Beellionaire club, a new NFT project, announce the launch of their latest endeavor: 7777 unique NFTs, created to work together to serve the same purpose of creating an innovative art, gaming and utility project.

This is the project’s first venture into the evolving world of non-fungible tokens (NFTs) pixel art.

 

The exclusive Honeybee collection will become available on Friday, 25.2.2022, at 12 pm ET / 5 pm GMT on the Ethereum blockchain. The 7777 stunning NFTs, created on ERC-721 contract, are priced at 0.05 ETH. Exclusive whitelist sale will become available on Wednesday, 23.2.2022, at 12 pm ET / 5 pm GMT on the Ethereum blockchain, priced at 0.04 ETH..

 

Their entire collection of Honeybee NFTs are all 100% unique. They are randomly generated by Beellionaire’s own artist, allowing each NFT a diversified trait rarity.

 

Each owned Honeybee generates 10 $NECTAR/day, which can be used to redeem different rewards including ticketed social events, giveaways, and metaverse items.

 

“Beellionaire club was founded to achieve simplicity and bring all that the NFT space has to offer on one unique platform, so it’s only fitting for us to bring this legacy into the world of NFTs, as said by the project founders. “Our up-and-coming NFT drop is more than just pixel art. We created this new collection for to bring value to the whole project with the tokenized utility system in order to reward long-term holders and to show them that they are an equal part of the project as the founders themselves. This three-phase project is not only inspired by CyberKongz, but also represents a wide variety of the world of Tokenized projects.”

 

Beellionaire club has made it their mission to package up everything NFTs have to offer in the same project. They’re doing this by distributing them in various phases.

 

Beellionaire club provides an inventive solution to remain relevant in the future NFT space.

 

In the early stages of NFTs, they found inspiration for Phase 1 of their project. Specifically, in the beauty of 8-bit pixel art, which has had much success—as is the case with projects like CryptoPunks.

 

The beauty of Beellionaire club’s art lies in the simplicity it provides. It’s on this foundation from which they’ll confidently launch Phase 1, which is utility based.

 

Community-oriented projects like Beellionaire club are setting out to revolutionize the DAO project concept by empowering their community.

 

While overpromising and overhyping have been the downside of many projects in the NFT space, Beellionaire club has made it work for them by providing people with clear and transparent plans for the future of the project.

 

The strategy behind Phase 2 is oriented towards creating innovative art by 10 designers. These designers will compete to be selected by The Hive community for the next Killerbee NFT drop.

 

Giving back to the people is one of the core values of the Beelionnaire club project. It’s on this foundation that trust, transparency, and collaboration are built within the community over time.

 

Beellionaire club is also setting a great example of generosity as shown in their commitment to donating to various bee charity organizations. For Beellionaire club community there will be poll organized, where the community will decide which specific organizations will receive the funds.

 

In Phase 3, community growth and community wallet will enable Beellionaire club to find its place alongside the biggest gaming and metaverse projects. Beellionaire club will be launched onto the metaverse platform chosen by The Hive.

 

Although it’s a substantial goal to achieve, it’s only a question of time when we will see Beellionaire club and similar projects taking off.

 

The team members are more than happy to organize AMAs and other social events where they are more than happy to answer all your questions. For more information, check out their Discord server.

 

Business Name: Binary Dash d.o.o

Contact Person: Bruno Poslon

Email : bruno@binarydash.eu

Website: https://www.beellionaire.io/

Country : Croatia

 

For more information visit :

Website: https://www.beellionaire.io/

Discord:  https://discord.com/invite/ngPpGhknqJ

Twitter: https://twitter.com/BeellionaireNFT

Instagram: https://www.instagram.com/beellionaire_nft/

 

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NASDAQ Company offers Life Saving Medical Advances; AI & Immunotherapy for Cancer & Immune Related Diseases Including COVID-19: Avalon GloboCare Corp. (NASDAQ: AVCO)

  • Clinical-Stage CellTech Developer Dedicated to Immune Effector Cell Therapy and Exosome Technology.
  • Introducing Life Saving COVID-19 Diagnostics and Therapeutics.
  • New Treatment for Deadly Cytokine Storm in COVID-19 Patients.
  • Novel Technology to Efficiently Synthesize & Study Previously Difficult to Work With Drug Targets.
  • Technology Will Facilitate Drug Design for Cancer & Immune Diseases.
  • Study Published in September 2021 Issue of Journal Membranes.
  • Leveraging Avalon’s existing Flash-CARTM technology platform to develop next-generation mRNA-based CAR-NK cellular therapeutics
  • Clinical development of CAR-NK cell therapy planned in collaboration with the Company’s clinical partner, Lu Daopei Hospital, as a potential treatment for hematologic malignancies and other unmet medical areas
  • Appoints Dongfang Liu, Ph.D., a world-class scientist and expert in CAR-NK technology, to Avalon’s Scientific and Clinical Advisory Board

FREEHOLD, N.J., Feb, 2022 (Avalon GloboCare Corp. (NASDAQ: AVCO), a leading global developer of cell-based technologies and therapeutics, announced today that the Company is expanding its cellular immuno-oncology program with the addition of novel Chimeric Antigen Receptor – Natural Killer (CAR-NK) cell therapies.

Natural killer (NK) cells constitute an important component of the immune system. NK cells seek out abnormal cells, including cancerous cells, and destroy them. However, cancer cells are often capable of “masking” themselves to evade attack by NK cells. By adding a “Chimeric Antigen Receptor” (CAR) to a patient’s own or universal-donor NK cells, these engineered CAR-NK cells are designed to “unmask,” recognize and destroy a patient’s specific tumor surface targets.

Avalon is leveraging its mRNA-based FLASH-CAR™ platform to develop autologous and universal (“off-the-shelf”) CAR-NK technology and cellular therapies for the potential treatment of hematologic malignancies and solid tumors. Avalon plans to expand its clinical program in collaboration with its major clinical trial partner, the Lu Daopei Hospital.

The new CAR-NK therapies in development are intended to build upon and complement AVA-011, Avalon’s lead CAR-T candidate, part of the Company’s proprietary mRNA-based FLASH-CAR™ platform. AVA-011 is currently at the IND-enabling, process development stage, which is expected to produce clinical-grade CAR-T cells for an upcoming clinical trial in patients with hematological malignancies. The platform uses next generation CAR technology to modify patients’ T or universal-donor NK cells using a ribonucleic acid (RNA)-based platform rather than a viral vector, allowing for more rapid and lower-cost bio-manufacturing of the cell therapy products.

To further strengthen its CAR-NK development capabilities, Avalon has appointed Dr. Dongfang Liu to its Scientific and Clinical Advisory Board. Dr. Liu is currently an Associate Professor and Director of Immunoassay Development Program at the Department of Pathology, Immunology and Laboratory Medicine at The Rutgers University New Jersey Medical School. Dr. Liu’s research expertise is focused on the immunobiology of NK and CAR-NK, with more than 20 years of experience in NK cell research. Dr. Liu is a prolific author in top-tier journals including Nature Immunology, Immunity, Nature Medicine, Nature Communications, JACI, and PNAS. Dr. Liu also serves on the editorial boards of several scientific journals and as a reviewer for scientific journals and grant agencies.

“CAR-NK represents a powerful and innovative tool in the fight against cancer, and we believe our mRNA-based FLASH-CAR™ platform will enable us to develop best-in-class therapies,” said David Jin, M.D., Ph.D., President and Chief Executive Officer of Avalon GloboCare. “We are especially pleased to welcome Dr. Dongfang Liu to our Scientific and Clinical Advisory Board. Dr. Liu will become an invaluable part of the team in expanding and supporting Avalon’s pipeline. We also appreciate the support of our world-class clinical partners, including the researchers and clinicians at the prestigious Lu Daopei Hospital, as we develop our cellular immuno-oncology programs for hematologic malignancies as well as other unmet medical needs,” added Dr. Jin.

Avalon GloboCare Corp. (NASDAQ: AVCO) is a clinical-stage, vertically integrated, leading CellTech bio-developer dedicated to advancing and empowering innovative, transformative immune effector cell therapy, exosome technology, as well as COVID-19 related diagnostics and therapeutics. AVCO also provides strategic advisory and outsourcing services to facilitate and enhance its clients' growth and development, as well as competitiveness in healthcare and CellTech industry markets. Through its subsidiary structure with unique integration of verticals from innovative R&D to automated bioproduction and accelerated clinical development, AVCO is establishing a leading role in the fields of cellular immunotherapy (including CAR-T/NK), exosome technology (ACTEX™), and regenerative therapeutics.

  • Advanced Filtration Tech Could Help Stop Life-Threatening Cytokine Storm in COVID-19 Patients

Cytokine storm has made frequent appearances in the news lately as a life-threatening complication in patients suffering from COVID-19. The condition is an inflammatory syndrome triggered by hyperactivation of immune cells that can significantly impact the patient’s chances of making a full recovery or surviving the infection at all.

Fortunately, AVCO has already been developing a range of therapies that have the potential to help target cytokine storm and other risk factors that make the widespread virus so difficult to get under control.

What Is Cytokine Storm?

The immune system uses cytokines to perform a variety of important tasks from clotting blood to triggering antibody production. When overworked — as can happen when the body is fighting off an aggressive, difficult disease like COVID-19 or is being treated with therapies designed to activate an immune response — that same immune system can end up producing too many cytokines. When the ones that trigger an inflammatory response are produced in excess, the cytokines trigger severe inflammatory symptoms, damage healthy tissue, and can even cause multiple organs to fail, leading to death.

AVCO AVA-Trap™ Already Targets Cytokine Storm

Because cytokine storm is a common risk factor in many cancer therapies, the oncology-focused AVCO was already hard at work on a way to calm down cytokine storms. The AVCO AVA-Trap™ therapeutic program was developed to target this potentially fatal complication. By using cytokine receptor proteins, the AVA-Trap™ program could dampen the release of cytokine, essentially filtering out the excess cytokines.

When COVID-19 started to spread through populations around the globe in 2020, doctors soon realized that the virus could induce a cytokine storm and that, when it did, the chances of that patient surviving grew slim. AVCO moved quickly to file and expanded patent for the proprietary filtration technology so it could be used to help COVID patients increase their chances of recovering from the disease.

AVCO Launches Full-Scale Plan to Tackle COVID-19 Pandemic

In addition to leveraging its existing AVA-Trap™ program to help combat cytokine storm and improve patient outcomes, AVCO also began working on a slate of other tools doctors can use to keep the evolving virus at bay.

In partnership with Adial Pharmaceuticals Inc. (NASDAQ: ADIL), AVCO is distributing a rapid diagnostics test that can detect multiple COVID antibodies with between 92.9% and 98.6% accuracy in just 10 minutes. Using the AVCO existing global distribution network, the 2 companies are able to make this rapid and highly accurate test available to healthcare providers worldwide.

In another partnership with Austria’s University of Natural Resources and Life Sciences (BOKU), AVCO is working on an intranasal spray vaccine for COVID-19.  Based on innovative S-layer technology that creates uniform, repetitive protein structures, the vaccine could become a highly effective formula in a format that people could self-administer — reducing the burden on healthcare providers to individually vaccinate the world’s population and reducing barriers to access for people with mobility challenges or who live too far from the nearest vaccine administration site.

Finally, AVCO began practical testing for its allogeneic MSC-based cellular therapy (ACETEX™), which could treat the acute respiratory distress syndrome (ARDS) and multisystem inflammatory syndrome that can also come with severe cases of COVID-19 infection and, like cytokine storm, significantly increase the risk of mortality. ARDS alone has been the cause of death in 70% of fatal COVID-19 cases where an aggressive inflammatory response happens.

ACETEX™ uses mesenchymal stromal cells taken from bone marrow, fat tissue, or other tissue types and adapts them to help moderate the body’s immune system response. Because cytokine storm, ARDS, and multisystem inflammatory syndrome in COVID-19 patients are all triggered by a hyperactive immune response, the potential ACETEX™ has for better regulating the immune response could offer a reliable treatment option to stop these complications in their tracks and prevent them from progressing to a fatal stage.

  • AVCO and University of Natural Resources and Life Sciences (BOKU) Co-develop Innovative In-Silico Technology, Enabling the Design and Synthesis of Novel Cell Membrane Receptor Targets for Cancer and Immune-Related Diseases

On October 7th AVCO announced co-development of a novel, cell-free, in-silico system to facilitate the Company’s drug development efforts, together with the Institute for Synthetic Bioarchitectures at the University of Natural Resources and Life Sciences (BOKU) in Vienna, Austria. A study of the new technology was featured in the September 2021 issue of Membranes, an international, peer-reviewed journal.

The new AVCO technology reveals that difficult-to-study cell membrane proteins can be efficiently expressed in a cell-free system, allowing for their evaluation as potentially druggable targets. The technology expands Avalon’s ability to design and produce novel membrane proteins—including receptors found on the surface of immune cells and cancer cells that are important for cell signaling and diseases such as cancer—providing Avalon an efficient tool to screen and optimize potential therapeutic targets.

Proteins function within cells and are also present on cell surfaces, embedded within the cell’s outer membrane. These membrane proteins include cell surface receptors that function in cell signaling and regulation of communication with other cells and tissues. These molecules are important drug targets and include receptors on immune cells such as T-cells for the development of cellular immunotherapies.

The researchers used computer-based models, developed at the University of Vienna, to identify factors that optimize the expression of membrane proteins in a cell-free, in-silico system, resulting in high protein yield. The AVCO study demonstrated the success of this method by showing the ability to manipulate and express a drug target membrane protein, a human voltage-dependent anion channel, at high yield.

The use of this novel AVCO technology can improve knowledge about receptors and other membrane proteins to better understand the biology of drug targets and to develop novel therapies, including immunotherapies for cancer.

The new technology is a direct result of a collaboration between AVCO and researchers at BOKU, Vienna, the University of Vienna, the Science for Life Laboratory within the Division of Nanobiotechnology at the KTH Royal Institute of Technology in Stockholm, Sweden and the Department of Biochemistry at the King Abdulaziz University in Jeddah, Saudi Arabia.

For more information on Avalon GloboCare Corp. (NASDAQ: AVCO) visit:

http://www.avalon-globocare.com  

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Lisa Bree Hoggarth, the Only supermodel in the world and reincarnation of Marilyn Monroe opens up about sexual harassment in her prior career as a car sales consultant and what she still faces in modelling. “I shouldn’t have taken the role at Nissan in 2017, the General Manager showed warning signs by continuing to peer down my top inappropriately at the interview. I felt desperate for work and overlooked the red flag at the beginning.” Lisa went on to experience verbal abuse from the same general manager, six months later, yet she remains relatively silent about the ins and outs of what occurred.

“I’ve had photographers adjust my necklace near my cleavage and make comments such as, ‘I can’t believe you’re not popping out of that bikini top.’ I am learning to be a lot more assertive with not accepting these musings by these men. For example, the photographer that touched me could have told me, instead of leaning towards me. I can fix my own necklace. They must control their flirtations.” The only supermodel said she has offended a new photographer prior to shooting by putting the boundary in place that he not touch her. “This one reiterated that he was a professional and shook his head towards other photographers for acting in such a manner, he wasn’t warming to my ‘no touching of the only supermodel in the world policy.’” Marilyn Monroe if you didn’t know, is Lisa Bree Hoggarth but that’s recorded on Lisa’s social media. instagram.com/@lisahoggarthstyle.

“I told the man his comment was inappropriate in relation to my bust ‘popping out.’ Moreover he spoke rubbish about being someone who would help to find me work. He said he did campaign shoots for Nike, he didn’t live up to his word of being a good person and giving me work.” Lisa stresses professionalism in what she does and expects the same from those who she works with, “as a sex symbol it’s confronting because I must have boundaries in place. They should keep their eyes on the prize and in focus.”

 

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