Ahmedabad, Gujarat, India, December 06, 2023 - Oral Submucous Fibrosis (OSMF), also known as fibrosis of the oral buccal mucosa, is a highly chronic and terribly debilitating disease that affects the mucous membrane lining the mouth. We often see it as a characterisation of excessive collagen deposition leading to a hardening and shrinking of the oral tissues, leading to restrictive mouth opening and then risk of oral cancer. OSMF is primarily associated with the consumption ofSupari(betel nut) and excessive spicy food (capsine), a stimulant widely used in Southeast Asia and the Indian subcontinent, along with chewing tobacco, eating paan masala and Gutkha.


The most common symptoms of OSMF include:

  • Restricted mouth opening, also known as trismus, due to the tightening of oral buccal tissues
  • Burning sensation in the mouth during eating food.
  • Frequently Oral Ulceration in Tongue and Mouth.
  • Difficulty in chewing and swallowing
  • Altered taste perception
  • Whitening of the oral mucosa
  • Smooth and shiny appearance of the oral mucosa


OSMF is considered a precancerous, premalignant condition, meaning it carries a significantly increased risk of developing into oral squamous cell carcinoma (OSCC) or Oral Cancer, which happens to be the most common type of disease occurring among OSMF patients.


Studies have shown that the risk of Oral Cancer in OSMF patients is 7 to 13 times higher than in the general population.


Early diagnosis and proper treatment of OSMF are crucial to prevent its progression to Oral Cancer. Prompt intervention by trained dentists can help manage and alleviate the symptoms, greatly improve oral function, and reduce the terrible risk of malignant transformation. Some general treatment options for OSMF include:

  • Cessation of areca nut, paan masala, khaini consumption.
  • Modification in diet.
  • Tropical medications to reduce inflammation and promote healing.
  • Oral physiotherapy to improve mouth opening and flexibility.
  • Surgery in severe cases to remove excess fibrous tissue.


OSMF and Oral Cancer share a complex relationship. The chronic inflammation and fibrosis associated with OSMF disrupt the normal cellular processes in the oral mucosa, making them more susceptible to genetic mutations that can lead to uncontrolled cell growth and oral cancer development. Additionally, the presence of OSMF can probablymask early signs of Oral Cancer, making it more challenging to detect the disease at an early stage.


Combating OSMF and Preventing Oral Cancer with Dr. Bharat Agravat's Mouth Opening Kit®


Since it is known that Oral Submucous Fibrosis or OSMF is a chronic and debilitating condition characterised by hardening and shrinking of oral tissues which poses a significant threat to oral health, it also behooves to share that Dr. Agravat Healthcare Ltd.:, led by the renownedand 18 award-winningIndian dentist Dr. Bharat Agravat with 25 years of experience, has developed world first an innovative and the most effective treatment solution – the OSMF Mouth Opening  DIY Kit– to combat OSMF and prevent its progression to oral cancer at home.


This comprehensive kit comprises four essential components:


OSMF Pops: These world first patented herbal lollipops, formulated with natural ingredients, help reduce inflammation and promote healing of the oral mucosa.


Unique Mouth Opener: This patented specially designed device facilitates effective mouth opening exercises, enhancing flexibility and range of motion.


OSMF Oral Gel: This topical gel, infused with anti-inflammatory and antioxidant properties, soothes irritation and accelerates the healing process.


OSMF Vita: These tablets, containing a blend of Lycopene Antioxident,Multivitamin, Multi-minerals address trismus (restricted mouth opening) for Joint Pain, Stiffness & Swelling

promote overall oral health.


Manufactured in a GMP Certified Facility, FDCA Approvedand CE certified, the OSMF Mouth Opening Kit offers a convenient and effective treatment option that can be seamlessly integrated into one's daily routine. The kit's portability allows for easy usage at home or while traveling.


Dr. Agravat's OSMF Mouth Opening Kit stands out as a valuable tool in the fight against OSMF and oral cancer. By addressing the root cause of OSMF and promoting healing, the DIY kit effectively nips oral cancer in the bud, safeguarding oral health and overall well-being.


In conclusion, Oral Submucous Fibrosis is a serious condition that demands attention and timely intervention. By understanding its symptoms, dangers, and connection to oral cancer, individuals can take proactive measures to prevent its progression and protect their oral health. Early diagnosis, cessation of risk factors, and appropriate treatment are essential to manage OSMF effectively and reduce the risk of developing oral cancer.



Dr. Agravat Healthcare Ltd is a leading pharmaceutical company in India with a strong focus on innovation and quality. The company manufactures a wide range of products, including oral care, personal care, beauty care, wellness, cancer, Ayurveda, and nutraceuticals. Dr. Agravat Healthcare Ltd is committed to making healthcare safer and more productive. The company isheadquartered in Ahmedabad, Gujarat, India, and has a global presence.



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